An adverse outcome pathway for lung surfactant function inhibition leading to decreased lung function
نویسندگان
چکیده
منابع مشابه
Reduced Lung Function and Progression to Prediabetes: A Prospective Study
Objective: Prediabetes is a state that people have blood glucose levels higher than normal but still not in diabetes range. There is a close relationship between impaired lung function and diabetes mellitus (DM). Reduced lung function can be present before the clinical evidence of diabetes or insulin resistance. Materials and Methods: The total number of subjects in this longitudinal study was ...
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Cystic fibrosis (CF) lung disease is primarily a disease of the small airways. We hypothesized that even in patients with normal lung function, a reduced surfactant function would be present and favor small airway obstruction. Bronchoalveolar lavages from 76 patients with CF (5-31 years, median 11) with well-conserved lung function (FEV1 94% predicted, range 78-121) and from 10 healthy control ...
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ژورنال
عنوان ژورنال: Current Research in Toxicology
سال: 2021
ISSN: 2666-027X
DOI: 10.1016/j.crtox.2021.05.005